Home » Best Cold And Flu Medicine For Adults [Complete List of 2021]

Best Cold And Flu Medicine For Adults [Complete List of 2021]

best cold flu medicine adults

Here we have brought together a list of the best cold and flu medicine for adults. Click the link below to go straight to a specific section.

Table of Contents

Disclosure: A few of the links on this blog are affiliate links. It means, at no additional cost, we will get a little commission if you click through and purchase.

Best Multi Symptom Cold Medicine

mucinex fast max cold and flu

It is an all in one maximum strength multi-symptom cold relief.

Each daytime cold and flu non-drowsy caplet gives:

So, daytime non-drowsy caplets help:

  • Relieve cough
  • Reduce chest congestion
  • Reduce nasal and sinus congestion
  • Relieve mucus buildup
  • Ease sinus pressure
  • Reduces fever
  • Relieve body pain
  • Reduce headache
  • Relieve sore throat

Also, every night time cold and flu caplet contains:

  • 325 mg of acetaminophen as a pain reliever and fever reducer
  • 5 mg of phenylephrine HCI as a decongestant medicine to relieve nasal congestion
  • 12.5 mg of diphenhydramine HCI (antihistamine) to suppress cough 

So, night time caplets are formulated to help relieve:

  • Coughing and sneezing
  • Nasal congestion
  • Stuffy nose
  • Fever
  • Body aches and pain
  • Headache
  • Runny nose
  • Itchy and sore throat

Price: as little as $0.43 per serving

best multi symptom cold medicine

Best Nighttime Cold Medicine

nyquil cold and flu - Nighttime Relief

NyQuil is one of the best nighttime cold and flu medicine to help you sleep. It is in the form of liquid to relieve symptoms of cold and flu.

Every 30 ml of NyQuil gives ingredients that are well known for being the best remedies for colds, such as:

  • 650 mg of acetaminophen to reduce fever and relieve pain
  • 20 mg of dextromethorphan HBr to control your coughing
  • 12.5 mg of doxylamine succinate as an antihistamine to relieve symptoms of the common cold, allergy, and hay fever, plus it helps you fall asleep and stay asleep [1]
  • 10 mg of phenylephrine HCl as a nasal decongestant to help relieve your stuffy nose

Long story short, this night time cold flu relief by Vicks can help temporarily relieve:

Price: as little as $0.71 per serving

best nighttime cold medicine

Best daytime cold and flu Medicine

ValuMeds Non-Drowsy Cold and Flu Multi-Symptom Relief

This product is formulated to be non drowsy and relieve cold or flu symptoms. So that you can stay focused and alert during the day.

Some users reported that it works fast and well to relieve breathing difficulties. Also, it is a budget alternative.  

Each daytime cold and flu soft gel contains:

  • 325 mg of acetaminophen 
  • 10 mg of dextromethorphan HBr 
  • 5 mg of phenylephrine HCL 

So, it is one of the otc cold medicine that helps relieve cold symptoms like:

  • Cough 
  • Pain
  • Nasal decongestant
  • Joint and muscle aches
  • Sore throat 
  • Running nose
  • Sneezing

Price: as little as $0.17 per serving

best daytime cold medicine

Best Head Cold Medicine

nyquil severe cold and flu

DayQuil/NyQuil is one of the best over counter cold and flu medicine. It gives acetaminophen to relieve severe cold and flu symptoms such as:

  • Cough
  • Headache and stuffy head
  • Sore throat
  • Fever
  • Sinus pressure
  • Minor aches and pains
  • Chest and nasal congestion 
  • Sneezing
  • Runny nose

Also, users say each daytime non drowsy red pill helps wake up and do your job. Plus, every blue pill helps get a full night of sleep.

So, it can be an effective cold medicine to fight both common and severe cold symptoms.

Price: as little as $0.35 per serving

best head cold medicine

Best Cough And Cold Medicine

Robitussin Cough, Cold, and Flu Medicine

Robitussin syrup for cough and cold contains guaifenesin to reduce chest congestion, infections, and irritants caused by cold.

Also, it contains dextromethorphan HBr that is a cough suppressant. As well, the cough-and-cold product gives acetaminophen and phenylephrine HCl to relieve:

  • Stuffy nose
  • Sinus and ear symptoms
  • Body aches and pains
  • Breathing difficulties
  • Nasal and chest congestion

Plus, it loosens and thins mucus that helps calm both wet and dry coughs.

Price: as little as $1.25 / Fl Oz

best cough and cold medicine

Best Cold Medicine For Stuffy Nose

Vicks Sinex SEVERE Nasal Spray

It is an effective nasal spray decongestant to relieve sinus pressure and nasal stuffiness.

Also, Vicks Sinex is an Over-the-counter nasal spray that helps upper respiratory allergies. Plus, it gives a 12-hour relief of sinus pressure and stuffy nose.

As well, some users say that it works instantly (about 10 minutes) to open swollen sinuses and relieve nasal congestion.

Price: as little as $14.95 

best cold medicine for stuffy nose

GoodSense Maximum Strength Nasal Decongestant PE

Each nasal decongestant PE tablet gives 10 mg of phenylephrine HCl.

It helps relieve sinus pressure and congestion caused by hay fever, the common cold, influenza, or an upper respiratory allergy.

Price: as little as $0.06 per serving

nasal decongestant tablet to relieve stuffy nose

Best Medicine For Sinus Cold

Boiron Sinuscalm Sinus Relief Tablets

It is one of the top cold medications to relieve sinus pain and stop runny nose.

Plus, it is a non-drowsy and homeopathic sinus Relief product. 

As well, it is non-habit forming and slightly melts under your tongue. 

Price: as little as $0.17 per tablet

best cold medicine for sinus cold

Mucinex Sinus-Max Max Strength Day & Night Liquid Gels

Each day time capsule loosens and thins mucus and relieves:

  • Sinus pressure
  • Congestion
  • Headache

Plus, each nighttime cold and flu relief helps reduce:

  • Nasal congestion
  • Sinus pressure
  • Pain
  • Runny nose
  • Sneezing
  • Coughing

Each daytime cold and flu relief contains:

  • 325 mg of acetaminophen
  • 10 mg of dextromethorphan HBr
  • 200 mg of guaifenesin 
  • 5 mg of phenylephrine HCl

Price: as little as $0.67 per tablet

Mucinex Sinus-Max to reduce sinus pressure and cold

Best Cold Medicine For High Blood Pressure

Coricidin HBP Cough And Cold Tablets

It is the best cold and flu medication for high blood pressure. It helps people with HBP to stop coughs and runny noses. 

Price: as little as $1.36 per serving

best cold medicine for high blood pressure

coricidin HBP cold and flu

It is another popular OTC cold and flu med for people with high blood pressure.

It works quickly to relieve:

  • Fever
  • Runny nose
  • Cough
  • Body aches and pains
  • Headache
  • Runny Nose and Sneezing

Price: as little as $12.40 

coricidin hbp cold and flu

Best Cold Medicine For Sore Throat

robitussin cold and flu - Severe Cough + Sore Throat Relief Medicine

It is the best medicine for flu and sore throat that contains acetaminophen and dextromethorphan HBr.

  • Works fast
  • Stops cough 
  • Relieves sore throat
  • Non-Drowsy 
  • Reduces Fever

Price: as little as $1.78 / Fl Oz

best cold medicine for sore throat

Genexa Cold Crush

It is an organic and non-GMO over the counter medicine for cough and cold as well as strep throat that relieves:

  • Congestion and mucus
  • Cough and sore throat
  • Runny nose and sneezing

Plus, each chewable tablet is non drowsy and contains:

  • Organic Aconitum napellus
  • Organic Allium cepa 
  • Organic Bryonia alba
  • Organic Euphrasia Officinalis
  • Organic Gelsemium sempervirens
  • Organic Nux vomica
  • Organic Pulsatilla
  • Organic Rhus Toxicodendron
  • Organic Sabadilla
  • Organic Carnauba Wax
  • Organic Compliant Natural Flavor
  • Organic Maltodextrin
  • Organic Rice Bran Extract
  • Organic Dextrose

Price: as little as $0.25 per servings

Genexa Cold Crush

Best Pre Cold Medicine

Zicam Cold Remedy Rapidmelts

It is the best cold and flu medicine for adults that gives zinc to shorten the length of colds.

Also, each tablet dissolves quickly is non-drowsy. Plus, it contains ingredients that are clinically proven to shorten and ease cold symptoms.

All you need to do when you feel a cold coming on is to take Zicam cold remedy. 

Price: as little as $0.40 per serving

Best Pre Cold Medicine

best decongestant for cold

ValuMeds Nasal Decongestant PE

  • Sinus Pressure Relief
  • Maximum Strength 
  • Fast-Acting
  • Helps Breathe Easier
  • Relieves Sinus Pain

Price: as little as $0.09 per serving

best decongestant for cold

other best medicine for cough and cold

tylenol cold and flu severe

Price: as little as $0.26 per serving

tylenol cold and flu

advil cold and flu

Price: as little as $0.40 per serving

advil cold and flu

alka seltzer plus cold and flu

Price: as little as $0.32 per serving

alka seltzer plus cold and flu

contac cold and flu

Price: as little as $6.99 

contac cold and flu

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